Medicine
Oncology
CNS Tumors
Treatment


Home > Disciplines > Medicine > Oncology > CNS Tumors > Treatment


Tumor Group




Overview




BLOOD-BRAIN BARRIER



Semyachkina-Glushkovskaya O, Kurths J, Borisova E, Sokolovski S, Mantareva V, Angelov I, Shirokov A, Navolokin N, Shushunova N, Khorovodov A, Ulanova M, Sagatova M, Agranivich I, Sindeeva O, Gekalyuk A, Bodrova A, Rafailov E.
Photodynamic opening of blood-brain barrier.
Biomed Opt Express. 2017 Oct 17;8(11):5040-5048. doi: 10.1364/BOE.8.005040. eCollection 2017 Nov 1.
Source | Abstract | Full text | Similar articles



DRUG DELIVERY



Shah V, Kochar P.
Brain Cancer: Implication to disease, therapeutic strategies and tumor targeted drug delivery approaches.
Recent Pat Anticancer Drug Discov. 2017 Nov 29. doi: 10.2174/1574892812666171129142023. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



IMMUNOTHERAPY


.

Bahreyni A, Ghorbani E, Fuji H, Ryzhikov M, Khazaei M, Erfani M, Avan A, Hassanian SM, Azadmanesh K.
Therapeutic potency of oncolytic virotherapy-induced cancer stem cells targeting in brain tumors, current status, and perspectives.
J Cell Biochem. 2018 Oct 15. doi: 10.1002/jcb.27661. [Epub ahead of print]
Source | Full text | Similar articles



.

Hoang-Minh LB, Mitchell DA.
Immunotherapy for Brain Tumors.
Curr Treat Options Oncol. 2018 Oct 11;19(11):60. doi: 10.1007/s11864-018-0576-3.
Source | Full text | Similar articles



.

Lieberman NAP, Vitanza NA, Crane CA.
Immunotherapy for brain tumors: understanding early successes and limitations.
Expert Rev Neurother. 2018 Mar;18(3):251-259. doi: 10.1080/14737175.2018.1425617. Epub 2018 Jan 11.
Source | Full text | Similar articles




Sampson JH, Maus MV, June CH.
Immunotherapy for Brain Tumors.
J Clin Oncol. 2017 Jun 22:JCO2017728089. doi: 10.1200/JCO.2017.72.8089. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Sayour EJ, Mitchell DA.
Immunotherapy for Pediatric Brain Tumors.
Brain Sci. 2017 Oct 21;7(10). pii: E137. doi: 10.3390/brainsci7100137.
Source | Abstract | Full text | Similar articles




Tsiatas M, Mountzios G, Curigliano G.
Future perspectives in cancer immunotherapy.
Ann Transl Med. 2016 Jul;4(14):273. doi: 10.21037/atm.2016.07.14.
Source | Abstract | Full text | Similar articles



NANOMEDICINE



Reynolds JL, Mahato RI.
Nanomedicines for the Treatment of CNS Diseases.
J Neuroimmune Pharmacol. 2017 Mar;12(1):1-5. doi: 10.1007/s11481-017-9725-x. Epub 2017 Feb 1.
Source | Abstract | Full text | Similar articles



R.A.N.O. RESPONSE CRITERIA



Wen PY, Chang SM, Van den Bent MJ, Vogelbaum MA, Macdonald DR, Lee EQ.
Response Assessment in Neuro-Oncology Clinical Trials.
J Clin Oncol. 2017 Jun 22:JCO2017727511. doi: 10.1200/JCO.2017.72.7511. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



CHILDHOOD BRAIN AND SPINAL CORD TUMORS



PDQ Pediatric Treatment Editorial Board.
Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ®): Patient Version.
PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-2017 Feb 8.
Source | Abstract | Full text | Similar articles




PDQ Pediatric Treatment Editorial Board.
Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ®): Patient Version.
PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-.2016 Aug 26.
Source | Abstract | Full text | Similar articles



.

Rutka JT.
Malignant Brain Tumours in Children : Present and Future Perspectives.
J Korean Neurosurg Soc. 2018 May;61(3):402-406. doi: 10.3340/jkns.2018.0044. Epub 2018 May 1.
Source | Abstract | Full text | Similar articles



RADIOTHERAPY


.

Baliga S, Yock TI.
Proton beam therapy in pediatric oncology.
Curr Opin Pediatr. 2019 Feb;31(1):28-34. doi: 10.1097/MOP.0000000000000724.
Source | Similar articles




Combs SE.
Does Proton Therapy Have a Future in CNS Tumors?
Curr Treat Options Neurol. 2017 Mar;19(3):12. doi: 10.1007/s11940-017-0447-4.
Source | Abstract | Full text | Similar articles



.

Grunert M, Kassubek R, Danz B, Klemenz B, Hasslacher S, Stroh S, Schneele L, Langhans J, Ströbele S, Barry SE, Zhou S, Debatin KM, Westhoff MA.
Radiation and Brain Tumors: An Overview.
Crit Rev Oncog. 2018;23(1-2):119-138. doi: 10.1615/CritRevOncog.2018025927.
Source | Abstract | Full text | Similar articles



RE-IRRADIATION


.

Rao AD, Rashid AS, Chen Q, Villar RC, Kobyzeva D, Nilsson K, Dieckmann K, Nechesnyuk A, Ermoian R, Alcorn S, MacDonald SM, Ladra MM, Ford EC, Winey BA, Figueiredo MLS, Chen MJ, Terezakis SA.
Reirradiation for Recurrent Pediatric Central Nervous System Malignancies: A Multi-institutional Review.
Int J Radiat Oncol Biol Phys. 2017 Nov 1;99(3):634-641. doi: 10.1016/j.ijrobp.2017.07.026. Epub 2017 Jul 28.
Source | Full text | Similar articles



.

Tsang DS, Laperriere NJ.
Re-irradiation for Paediatric Tumours.
Clin Oncol (R Coll Radiol). 2018 Oct 29. pii: S0936-6555(18)30464-3. doi: 10.1016/j.clon.2018.10.003. [Epub ahead of print]
Source | Full text | Similar articles



RADIOSURGERY


.

Mitrasinovic S, Zhang M, Appelboom G, Sussman E, Moore JM, Hancock SL, Adler JR, Kondziolka D, Steinberg GK, Chang SD.
Milestones in stereotactic radiosurgery for the central nervous system.
J Clin Neurosci. 2019 Jan;59:12-19. doi: 10.1016/j.jocn.2018.09.029. Epub 2018 Oct 26.
Source | Full text | Similar articles



STEREOTACTIC BRAIN BIOPSY


.

Callovini GM, Telera S, Sherkat S, Sperduti I, Callovini T, Carapella CM.
How is stereotactic brain biopsy evolving? A multicentric analysis of a series of 421 cases treated in Rome over the last sixteen years.
Clin Neurol Neurosurg. 2018 Nov;174:101-107. doi: 10.1016/j.clineuro.2018.09.020. Epub 2018 Sep 13.
Source | Full text | Similar articles



STEROIDS



Ly KI, Wen PY.
Clinical Relevance of Steroid Use in Neuro-Oncology.
Curr Neurol Neurosci Rep. 2017 Jan;17(1):5. doi: 10.1007/s11910-017-0713-6. Online 2017 Jan 30.
Source | Abstract | Full text | Similar articles



SURGERY


.

Bowden SG, Han SJ.
The Evolving Role of the Oncologic Neurosurgeon: Looking Beyond Extent of Resection in the Modern Era.
Front Oncol. 2018 Sep 25;8:406. doi: 10.3389/fonc.2018.00406. eCollection 2018.
Source | Full text | Similar articles



.

Díez Valle R, Hadjipanayis CG, Stummer W.
Established and emerging uses of 5-ALA in the brain: an overview.
J Neurooncol. 2019 Feb;141(3):487-494. doi: 10.1007/s11060-018-03087-7. Epub 2019 Jan 3.
Source | Full text | Similar articles



.

Fernandes Cabral DT, Zenonos GA, Nuñez M, Celtikci P, Snyderman C, Wang E, Gardner PA, Fernandez-Miranda JC.
Endoscopic Endonasal Transclival Approach for Resection of a Pontine Glioma: Surgical Planning, Surgical Anatomy, and Technique.
Oper Neurosurg (Hagerstown). 2018 Mar 12. doi: 10.1093/ons/opy005. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



.

Zattra CM, Zhang DY, Broggi M, Velz J, Vasella F, Seggewiss D, Schiavolin S, Bozinov O, Krayenbühl N, Sarnthein J, Ferroli P, Regli L, Stienen MN.
Repeated craniotomies for intracranial tumors: is the risk increased? Pooled analysis of two prospective, institutional registries of complications and outcomes.
J Neurooncol. 2018 Nov 24. doi: 10.1007/s11060-018-03058-y. [Epub ahead of print]
Source | Full text | Similar articles



THERANOSTICS




NONPROSTATIC MALIGNANCIES


.

Backhaus P, Noto B, Avramovic N, Grubert LS, Huss S, Bögemann M, Stegger L, Weckesser M, Schäfers M, Rahbar K.
Targeting PSMA by radioligands in non-prostate disease-current status and future perspectives.
Eur J Nucl Med Mol Imaging. 2018 May;45(5):860-877. doi: 10.1007/s00259-017-3922-y. Epub 2018 Jan 15.
Source | Abstract | Full text | Similar articles



.

Malik D, Kumar R, Mittal BR, Singh H, Bhattacharya A, Singh SK.
68Ga-Labeled PSMA Uptake in Nonprostatic Malignancies: Has the Time Come to Remove "PS" From PSMA?
Clin Nucl Med. 2018 Apr 23. doi: 10.1097/RLU.0000000000002103. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



TUMOUR TREATING FIELDS


.

Mirza FA, Shamim MS.
Tumour Treating Fields (TTFs) for Paediatric Brain Tumours, Brain Metastases and other Novel Applications.
J Pak Med Assoc. 2018 Nov;68(11):1729-1731.
Source | Full text | Similar articles



Laboratory investigations



Merkel O, Taylor N, Prutsch N, Staber PB, Moriggl R, Turner SD, Kenner L.
When the guardian sleeps: Reactivation of the p53 pathway in cancer.
Mutat Res. 2017 Jul;773:1-13. doi: 10.1016/j.mrrev.2017.02.003. Epub 2017 Feb 17.
Source | Abstract | Full text | Similar articles



Clinical investigations




Newly diagnosed tumors




RIDAFOROLIMUS



Pearson AD, Federico SM, Aerts I, Hargrave DR, DuBois SG, Iannone R, Geschwindt RD, Wang R, Haluska FG, Trippett TM, Geoerger B.
A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors.
Oncotarget. 2016 Oct 4. doi: 10.18632/oncotarget.12450. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



SURGERY



Roth J, Constantini S.
5ALA in pediatric brain tumors is not routinely beneficial.
Childs Nerv Syst. 2017 Mar 14. doi: 10.1007/s00381-017-3371-8. [Epub ahead of print]

Source | Abstract | Full text | Similar articles



Recurrent tumors




IMETELSTAT



Salloum R, Hummel TR, Kumar SS, Dorris K, Li S, Lin T, Daryani VM, Stewart CF, Miles L, Poussaint TY, Stevenson C, Goldman S, Dhall G, Packer R, Fisher P, Pollack IF, Fouladi M, Boyett J, Drissi R.
A molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study.
J Neurooncol. 2016 Jun 27. [Epub ahead of print]
Source | Abstract | Full text | Meeting abstract (2015)



PEDIATRIC TUMORS



Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH, Kramer K, Spasojevic I, Dunkel IJ.
A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
Pediatr Blood Cancer. 2016 Dec 30. doi: 10.1002/pbc.26409. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



.

Gorsi HS, Malicki DM, Barsan V, Tumblin M, Yeh-Nayre L, Milburn M, Elster JD, Crawford JR.
Nivolumab in the Treatment of Recurrent or Refractory Pediatric Brain Tumors: A Single Institutional Experience.
J Pediatr Hematol Oncol. 2018 Oct 23. doi: 10.1097/MPH.0000000000001339. [Epub ahead of print]
Source | Abstract | Similar articles



PEMBROLIZUMAB



Blumenthal DT, Yalon M, Vainer GW, Lossos A, Yust S, Tzach L, Cagnano E, Limon D, Bokstein F.
Pembrolizumab: first experience with recurrent primary central nervous system (CNS) tumors.
J Neurooncol. 2016 Jul 4. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



RE-IRRADIATION



Nieder C, Andratschke NH, Grosu AL.
Re-irradiation for Recurrent Primary Brain Tumors.
Anticancer Res. 2016 Oct;36(10):4985-4995.
Source | Abstract | Full text | Similar articles



TEMOZOLOMIDE



Egan G, Cervone KA, Philips PC, Belasco JB, Finlay JL, Gardner SL.
Phase I study of temozolomide in combination with thiotepa and carboplatin with autologous hematopoietic cell rescue in patients with malignant brain tumors with minimal residual disease.
Bone Marrow Transplant. 2016 Apr;51(4):542-5. doi: 10.1038/bmt.2015.313. Epub 2016 Jan 4.
Source | Abstract | Full text | Similar articles