Medicine | Oncology
Prostate cancer
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Prediction tool: Positive biopsy cores


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Antunes AA, Dall'Oglio MF, Sant'Anna AC, Paranhos M, Leite KR, Srougi M.
Prognostic value of the percentage of positive fragments in biopsies from patients with localized prostate cancer.
Int Braz J Urol. 2005 Jan-Feb;31(1):34-41.
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Capitanio U, Briganti A, Shariat SF, Karakiewicz PI.
The importance of the quantification of the extent of cancer in prostatic biopsies in prediction of biochemical recurrence: a global perspective.
Eur Urol. 2008 Oct;54(4):717-9. doi: 10.1016/j.eururo.2008.07.034. Epub 2008 Jul 21.
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Freedland SJ, Terris MK, Csathy GS, Kane CJ, Amling CL, Presti JC Jr, Dorey F, Aronson WJ; Search Database Study Group.
Preoperative model for predicting prostate specific antigen recurrence after radical prostatectomy using percent of biopsy tissue with cancer, biopsy Gleason grade and serum prostate specific antigen.
J Urol. 2004 Jun;171(6 Pt 1):2215-20. DOI: http://dx.doi.org/10.1097/01.ju.0000124463.13319.0a
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Freedland SJ, Aronson WJ, Terris MK, Kane CJ, Amling CL, Dorey F, Presti JC Jr.
The percentage of prostate needle biopsy cores with carcinoma from the more involved side of the biopsy as a predictor of prostate specific antigen recurrence after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database.
Cancer. 2003 Dec 1;98(11):2344-50. Epub 2003 Oct 20.
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Freedland SJ, Aronson WJ, Terris MK, Kane CJ, Amling CL, Dorey F, Presti JC Jr; SEARCH Database Study Group.
Percent of prostate needle biopsy cores with cancer is significant independent predictor of prostate specific antigen recurrence following radical prostatectomy: results from SEARCH database.
J Urol. 2003 Jun;169(6):2136-41. DOI: http://dx.doi.org/10.1097/01.ju.0000065588.82511.06
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Freedland SJ, Aronson WJ, Csathy GS, Kane CJ, Amling CL, Presti JC Jr, Dorey F, Terris MK; SEARCH Database Study Group.
Comparison of percentage of total prostate needle biopsy tissue with cancer to percentage of cores with cancer for predicting PSA recurrence after radical prostatectomy: results from the SEARCH database.
Urology. 2003 Apr;61(4):742-7. DOI: http://dx.doi.org/10.1016/S0090-4295(02)02525-6
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Freedland SJ, Csathy GS, Dorey F, Aronson WJ.
Clinical utility of percent prostate needle biopsy tissue with cancer cutpoints to risk stratify patients before radical prostatectomy.
Urology. 2002 Jul;60(1):84-8. DOI: http://dx.doi.org/10.1016/S0090-4295(02)01660-6
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Freedland SJ, Csathy GS, Dorey F, Aronson WJ.
Percent prostate needle biopsy tissue with cancer is more predictive of biochemical failure or adverse pathology after radical prostatectomy than prostate specific antigen or Gleason score.
J Urol. 2002 Feb;167(2 Pt 1):516-20. DOI: http://dx.doi.org/10.1016/S0022-5347(01)69076-1
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Graefen M, Noldus J, Pichlmeier U, Haese A, Hammerer P, Fernandez S, Conrad S, Henke R, Huland E, Huland H.
Early prostate-specific antigen relapse after radical retropubic prostatectomy: prediction on the basis of preoperative and postoperative tumor characteristics.
Eur Urol. 1999 Jul;36(1):21-30. https://doi.org/10.1159/000019922
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Hamada R, Nakashima J, Ohori M, Ohno Y, Komori O, Yoshioka K, Tachibana M.
Erratum to: Preoperative predictive factors and further risk stratification of biochemical recurrence in clinically localized high-risk prostate cancer.
Int J Clin Oncol. 2016 Jan 8. [Epub ahead of print]
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Hamada R, Nakashima J, Ohori M, Ohno Y, Komori O, Yoshioka K, Tachibana M.
Preoperative predictive factors and further risk stratification of biochemical recurrence in clinically localized high-risk prostate cancer.
Int J Clin Oncol. 2015 Nov 19. [Epub ahead of print] DOI 10.1007/s10147-015-0923-3
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Harnden P, Shelley MD, Naylor B, Coles B, Mason MD.
Does the extent of carcinoma in prostatic biopsies predict prostate-specific antigen recurrence? A systematic review.
Eur Urol. 2008 Oct;54(4):728-39. doi: 10.1016/j.eururo.2008.06.068. Epub 2008 Jun 26.
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Kır G, Seneldir H, Gumus E.
Outcomes of Gleason score 3 + 4 = 7 prostate cancer with minimal amounts (<6%) vs ≥6% of Gleason pattern 4 tissue in needle biopsy specimens.
Ann Diagn Pathol. 2016 Feb;20:48-51. doi: 10.1016/j.anndiagpath.2015.10.013. Epub 2015 Dec 2.
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San Francisco IF, Regan MM, Olumi AF, DeWolf WC.
Percent of cores positive for cancer is a better preoperative predictor of cancer recurrence after radical prostatectomy than prostate specific antigen.
J Urol. 2004 Apr;171(4):1492-9. DOI: http://dx.doi.org/10.1097/01.ju.0000118690.05943.c0
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